Potential Drug-Drug Interactions With Tyrosine Kinase Inhibitors
نویسندگان
چکیده
منابع مشابه
Metabolism-related pharmacokinetic drug−drug interactions with tyrosine kinase inhibitors: current understanding, challenges and recommendations
Drug-drug interactions (DDIs) occur when a patient's response to the drug is modified by administration or co-exposure to another drug. The main cytochrome P450 (CYP) enzyme, CYP3A4, is implicated in the metabolism of almost all of the tyrosine kinase inhibitors (TKIs). Therefore, there is a substantial potential for interaction between TKIs and other drugs that modulate the activity of this me...
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ژورنال
عنوان ژورنال: Annual for Hospital Pharmacy
سال: 2019
ISSN: 2367-8763
DOI: 10.14748/ahp.v5i1.6059